寝ても疲れが取れないとき

Nutritional Modulation of Sleep Latency, Duration, and Efficiency: A Randomized, Repeated-Measures, Double-Blind Deception Study.

• 参加者 16人
• 24歳前後の男女 16名
• 3日間

原文よりThe intervention trial reduced sleep onset latency (-24 ± 25 min; P = 0.002), increased total sleep time (22 ± 32 min; P = 0.01), and increased sleep efficiency (2.4% ± 3.9%; P = 0.03), while also reducing morning sleepiness ( P = 0.02).

Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.

• 参加者 80人
• 35-55歳の睡眠問題のある成人 80名
• 1g/日 21日間

原文よりThe MgT group maintained good sleep quality and daytime functioning, while placebo declined.

The effects of magnesium L-threonate (Magtein®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial.

• 参加者 100人
• 睡眠に不満を感じている18〜45歳の成人 100名
• Magtein® 2g/日 6週間

原文よりBased on self-report measures, there was a greater improvement in sleep-related impairment (p = 0.043), but no group differences in changes in sleep disturbances (p = 0.316), restorative sleep (p = 0.439), or general wellbeing (p = 0.436); although in a subset of participants with more severe sleep-related problems, group differences in sleep-disturbances were identified (p = 0.031).

The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.

• 参加者 46人

原文よりSupplementation of magnesium appears to improve subjective measures of insomnia such as ISI score, sleep efficiency, sleep time and sleep onset latency, early morning awakening, and likewise, insomnia objective measures such as concentration of serum renin, melatonin, and serum cortisol, in elderly people.

Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.

• 不安や不眠の症状がある人々（個別研究は個別に対象者が違い、異質性あり）

原文よりThe majority of included studies demonstrated improvement in at least one sleep- or anxiety-related parameter. Five out of eight sleep-related studies reported improvements in sleep parameters, while two studies reported no improvements, and one reported mixed results.

Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study.

• 参加者 3,964人
• CARDIA研究の参加者 3,964名
• 食事およびサプリメントによる摂取量 (ベースラインから20年間の追跡)

原文よりAfter adjustment for potential confounders, Mg intake was borderline associated with better sleep quality [highest quartile (Q4) vs. intake quartile (Q1): odds ratio (OR) = 1.23; 95% CI = 0.999, 1.50, ptrend = 0.051].

The sleep-enhancing effect of valerian inhalation and sleep-shortening effect of lemon inhalation.

• ラット

原文よりa significant shortening in sleep latency and a significant prolonging in total sleep time were observed with valerian inhalation

Critical evaluation of the effect of valerian extract on sleep structure and sleep quality.

• 参加者 16人
• 精神生理学的な不眠症の患者 16名

原文よりIn comparison with the placebo, slow-wave sleep latency was reduced after administration of valerian (21.3 vs. 13.5 min respectively, p<0.05).

Valerian Root in Treating Sleep Problems and Associated Disorders-A Systematic Review and Meta-Analysis.

• 参加者 6,894人
• 7-80歳の被験者を含む多様な研究対象 (n=6,894)

原文よりIn conclusion, valerian could be a safe and effective herb to promote sleep and prevent associated disorders.

Standardized Extract of Valeriana officinalis Improves Overall Sleep Quality in Human Subjects with Sleep Complaints: A Randomized, Double-Blind, Placebo-Controlled, Clinical Study.

• 参加者 72人
• 睡眠の悩みを持つ成人 72名

原文よりVE supplementation significantly improved various subjective and objective parameters of sleep in young subjects with mild insomnia symptoms, such as overall sleep quality, sleep latency, sleep efficiency, and total sleep time.