- There is one research report on the possibility that milk peptide is related to sleep quality.
- The evidence score is 39, and reliability is considered low.
- This information is relevant to people who keep records of their sleep condition.
Milk peptide (casein hydrolysate) is a component obtained by breaking down casein.
It is casein, a protein contained in milk, broken down into smaller pieces through a method called hydrolysis.
Milk peptide (casein hydrolysate) is casein, a component contained in milk, broken down into small pieces through processes such as digestion. In the research data, it is treated under the name "Alpha-s1 Casein Hydrolysate (ACH)."
It has been suggested that milk peptide may be related to sleep quality. In this research, several indicators of sleep condition were investigated.
Specifically, the length of time spent sleeping and sleep efficiency, among other things, were examined. Confirmation was also made regarding the time it takes to fall asleep and the frequency of waking up after having once fallen asleep.
In technical terms, changes such as an improvement in sleep efficiency (SE: the proportion of time actually asleep during the sleep period) and a decrease in wake after sleep onset (WASO: the time from falling asleep once to the next awakening) have been reported. Sleep onset latency (the time required to fall asleep) is also mentioned.
This research was carried out targeting people with specific conditions. A small number of 48 people participated, from a community where people with sleep concerns gather.
The survey period was 28 days. The subjects were compared by taking a product containing milk peptide during one period, and a product without it during another period.
The method of this research is called a randomized controlled trial (RCT: a highly reliable research method that randomly divides participants to compare effects). Furthermore, it took the form of a crossover trial (a method in which the same person experiences different conditions in sequence, to suppress the effect of individual differences), in which the same people experienced both conditions. In addition, to maintain the objectivity of the survey, a double-blind method (a method in which neither the participants nor the researchers know which ingredient is being taken) was used, and a placebo (an ineffective substance indistinguishable from the real thing) was set as the comparison.
This information is based on a single research report. Therefore, this result cannot be said to apply to everyone. The evidence score is shown as a figure of 39, and reliability is considered low.
One reason for this is that there is only 1 study, and the number of participants is limited to 48. As scientific knowledge, it is necessary to understand that this is still a stage that cannot yet be called certain.
It is also conceivable that individual differences may appear in the research results. Milk peptide may not suit everyone, and there are people for whom the expected result does not occur. Because what is known at present is limited, it is best not to expect too much, and to regard this as merely one piece of research data.
| Study | Design | Number of Participants | Duration | Main Result |
|---|---|---|---|---|
| Nutrients (2019, PMID:31252661) | Randomized controlled trial (RCT) | 48 people | 28 days | A positive effect was reported |
The research subjects were 48 Korean community residents with poor sleep quality.
Because the subjects were in a state of poor sleep quality, this serves as material for considering your own sleep situation.
This research is based on 1 randomized controlled trial (RCT).
The evidence score is 39, and reliability is considered limited.
The fact that there were 48 research subjects, among other things, is cited as a limitation of the research.
What effect has milk peptide (casein hydrolysate) been shown to have on sleep quality?
Research has been reported showing a positive effect on sleep quality. Specifically, an increase in total sleep time and sleep efficiency, as well as a decrease in sleep latency and wake after sleep onset, have been shown.
What kind of people were included in the research on milk peptide (casein hydrolysate)?
Korean community residents with poor sleep quality were included.
How reliable is the research on milk peptide (casein hydrolysate)?
Reliability is reported to be limited.
It has been suggested that milk peptide (casein hydrolysate) may bring about some change in indicators related to sleep quality. However, because there is only 1 study and the number of participants is limited to 48, reliability is reported to be low.
Please remember that this content is merely one research case, and the same result does not occur in everyone. Why not take this opportunity to reflect on your own sleep condition?

